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Thread: Synthetic model of human tissue

  1. #1

    Synthetic model of human tissue

    I am looking for a material that has stress-strain relationships similar to human tissue (see attached figure). The tissue has a very low small strain Young's modulus (around 10kPa), but increases quickly with strain.

    We've had some success matching the low-strain Young's modulus using a soft silicone with silicone thinner. However, this material does not possess the nonlinearity of human tissue.

    Does anyone have any suggestions for a material (or additive) that could be used in this application?



    Thanks!


    Douglas
    Attached Images Attached Images

  2. #2
    Join Date
    2000-02
    Location
    Boston, USA
    Posts
    3,280
    That is a difficult one. I would perform a literature search to see if you can find an references on the subject.

    You might be able to obtain the desired behavior using a composite structure consisting of a mesh-like (e.g. non-woven) material in a silicone matrix.

    -Jorgen
    Jorgen Bergstrom, Ph.D.
    PolymerFEM Administrator

  3. #3

    Synthetic Human Tissues and Body Parts

    Check out Syndaver Labs (www.syndaver.com). I am not sure exactly what your application is but they might be able to help you.

    Allie

  4. #4
    [QUOTE=douglascook;5146.....but increases quickly with strain.
    ....this material does not possess the nonlinearity of human tissue.
    ....[/QUOTE]


    Hi Douglas

    Biological tissues usually follow a strain hardening behavior and that's completely natural and a should-be, I believe.
    Why don't you use different Abaqus Built-in hyperelastic material models? Ogden or Mooney-rivlin forms can mimic the exp. data quite well I'm sure, if their application can be justified well. You may also like to start from Neo-hookean form, why not?


    Cheers,
    Amir

  5. #5
    Join Date
    2009-08
    Location
    Boston
    Posts
    1

    Ogden model

    Hi Douglas,

    I would suggest using the Ogden model for the plot u have attached. I had tested some animal tissue and found that the Ogden model fits pretty well for tissues.
    -a

  6. #6
    Hello,
    Many perfumes on the shelves in regular chemists, duty free and department stores are made with synthetic chemicals and are, rarely, just aromatherapy oils, despite what the label says. Labels can make claims that are not backed up in the contents of the perfume. 'Natural' is a widely abused term in the personal care industry, as is 'nature' frequently used where there is precious little natural about the contents.
    Thanks

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