This file summarizes the predictive capabilities of a number of different failure model approaches for UHMWPE. Abstract: Mechanical failure of UHMWPE components is one of the major factors controlling the lifetime of total joint arthoplasties. UHMWPE failures are often introduced at a micro-scale by wear and contact fatigue. Previous attempts to analytically predict the clinically observed damage, wear and fatigue failure modes have met limited success due to complicated interaction between microstructure deformations and continuum level stresses. The goal of the present study was to evaluate the utility of eight different failure models for predicting the failure of conventional and highly crosslinked UHMWPE under monotonic uniaxial as well as multiaxial loading conditions.